<?xml version="1.0"?> <!DOCTYPE bioml SYSTEM "bioml.dtd"> <bioml> <note> The following is a valid BIOML file describing the gene product that becomes human insulin. Note the differences between this example and the simple example given above. </note> <organism> <species>Homo sapiens</species> </organism> <protein comp="6xS[1]"> <name>Insulin</name> <subunit id="1" comp="1xP[1]D[3]+1xP[1]D[7]"> <peptide id="1" start="1" end="110"> <domain id="1" type="signal" start="1" end="24"/> <domain id="2" type="alpha-helix" start="33" end="46"/> <domain id="3" type="mature" start="25" end="54"> <name>Chain B</name> <aa type="C" at="31" to="96"/> <aa type="H" at="34"> <avariant at="34" type="D"/></aa> <aa type="C" at="43" to="109"/> <aa type="F" at="48"> <avariant at="48" type="S"/></aa> <aa type="F" at="49"> <avariant at="49" type="L"/></aa> </domain> <domain id="4" type="propeptide" start="55" end="89"> <name>Chain C</name> <aa type="R" at="89"> <avariant type="H"/> <avariant type="L"/></aa> </domain> <domain id="5" type="alpha-helix" start="91" end="95"/> <domain id="6" type="alpha-helix" start="102" end="108"/> <domain id="7" type="mature" start="90" end="110"> <name>Chain A</name> <aa type="V" at="92"> <avariant at="92" type="L"/></aa> <aa type="C" at="95" to="100"/> <aa type="C" at="96" to="31"/> <aa type="C" at="100" to="95"/> <aa type="C" at="109" to="43"/> </domain> MALWMRLLPL LALLALWGPD PAAAFVNQHL CGSHLVEALY LVCGERGFFY TPKTRREAED LQVGQVELGG GPGAGSLQPL ALEGSLQKRG IVEQCCTSIC SLYQLENYCN </peptide> </subunit> </protein> </bioml>