<?xml version="1.0"?>
<!DOCTYPE bioml SYSTEM "bioml.dtd">
<bioml>
<note>
The following is a valid BIOML file describing the gene
product that becomes human insulin. Note the differences between
this example and the simple example given above.
</note>
<organism>
<species>Homo sapiens</species>
</organism>
<protein comp="6xS[1]">
<name>Insulin</name>
<subunit id="1" comp="1xP[1]D[3]+1xP[1]D[7]">
<peptide id="1" start="1" end="110">
<domain id="1" type="signal" start="1" end="24"/>
<domain id="2" type="alpha-helix" start="33" end="46"/>
<domain id="3" type="mature" start="25" end="54">
<name>Chain B</name>
<aa type="C" at="31" to="96"/>
<aa type="H" at="34">
<avariant at="34" type="D"/></aa>
<aa type="C" at="43" to="109"/>
<aa type="F" at="48">
<avariant at="48" type="S"/></aa>
<aa type="F" at="49">
<avariant at="49" type="L"/></aa>
</domain>
<domain id="4" type="propeptide" start="55" end="89">
<name>Chain C</name>
<aa type="R" at="89">
<avariant type="H"/>
<avariant type="L"/></aa>
</domain>
<domain id="5" type="alpha-helix" start="91" end="95"/>
<domain id="6" type="alpha-helix" start="102" end="108"/>
<domain id="7" type="mature" start="90" end="110">
<name>Chain A</name>
<aa type="V" at="92">
<avariant at="92" type="L"/></aa>
<aa type="C" at="95" to="100"/>
<aa type="C" at="96" to="31"/>
<aa type="C" at="100" to="95"/>
<aa type="C" at="109" to="43"/>
</domain>
MALWMRLLPL LALLALWGPD PAAAFVNQHL CGSHLVEALY LVCGERGFFY
TPKTRREAED LQVGQVELGG GPGAGSLQPL ALEGSLQKRG IVEQCCTSIC
SLYQLENYCN
</peptide>
</subunit>
</protein>
</bioml>