| Chr | ORF | Gene | Observations | Best log(e) | EC | Description |
| A | YAR050W | FLO1 | 35 | -45.4 | 3 | Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p [Source:SGD;Acc:S000000084] |
| B | YBL014C | RRN6 | 66 | -61.5 | 3 | Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p [Source:SGD;Acc:S000000110] |
| B | YBR040W | FIG1 | 38 | -16.6 | 3 | Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating [Source:SGD;Acc:S000000244] |
| B | YBR148W | YSW1 | 39 | -22.6 | 3 | Protein required for normal prospore membrane formation; interacts with Gip1p, which is the meiosis-specific regulatory subunit of the Glc7p protein phosphatase; expressed specifically in spores and localizes to the prospore membrane [Source:SGD;Acc:S000000352] |
| B | YBR270C | BIT2 | 38 | -82.1 | 3 | Subunit of TORC2, a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; similar to Bit61p [Source:SGD;Acc:S000000474] |
| C | YCL036W | GFD2 | 52 | -34.8 | 3 | Protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation [Source:SGD;Acc:S000000541] |
| C | YCL058W-A | ADF1 | 74 | -22.4 | 3 | Transcriptional repressor encoded by the antisense strand of the FYV5 gene; negatively regulates transcription of FYV5 by binding to the promoter on the sense strand [Source:SGD;Acc:S000028518] |
| C | YCR018C | SRD1 | 33 | -22.6 | 3 | Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation [Source:SGD;Acc:S000000611] |
| C | YCR028C | FEN2 | 22 | -14.6 | 3 | Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph [Source:SGD;Acc:S000000623] |
| D | YDL020C | RPN4 | 26 | -25.7 | 3 | Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses [Source:SGD;Acc:S000002178] |
| D | YDR125C | ECM18 | 22 | -83.3 | 3 | Protein of unknown function, similar to Rlp24p [Source:SGD;Acc:S000002532] |
| D | YDR133C | YDR133C | 16 | -11.3 | 3 | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C [Source:SGD;Acc:S000002540] |
| D | YDR191W | HST4 | 27 | -13.8 | 3 | Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism [Source:SGD;Acc:S000002599] |
| D | YDR242W | AMD2 | 24 | -50 | 3 | Putative amidase [Source:SGD;Acc:S000002650] |
| D | YDR253C | MET32 | 22 | -19.3 | 3 | Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p [Source:SGD;Acc:S000002661] |
| D | YDR259C | YAP6 | 53 | -34.5 | 3 | Basic leucine zipper (bZIP) transcription factor; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; overexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation of expre of genes involved in carbohydrate metabolism [Source:SGD;Acc:S000002667] |
| D | YDR273W | DON1 | 35 | -33.3 | 3 | Meiosis-specific component of the spindle pole body, part of the leading edge protein (LEP) coat, forms a ring-like structure at the leading edge of the prospore membrane during meiosis II [Source:SGD;Acc:S000002681] |
| D | YDR306C | YDR306C | 22 | -80.6 | 3 | F-box protein of unknown function; interacts with Sgt1p via a Leucine-Rich Repeat (LRR) domain [Source:SGD;Acc:S000002714] |
| D | YDR315C | IPK1 | 21 | -47.1 | 3 | Inositol 1,3,4,5,6-pentakisphosphate 2-kinase, nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate (phytate), which is integral to cell function; has 2 motifs conserved in other fungi; ipk1 gle1 double mutant is inviable [Source:SGD;Acc:S000002723] |
| D | YDR524C-B | YDR524C-B | 11 | -8 | 3 | Putative protein of unknown function [Source:SGD;Acc:S000028739] |
| E | YEL073C | YEL073C | 15 | -15.2 | 3 | Putative protein of unknown function; located adjacent to ARS503 and the telomere on the left arm of chromosome V; regulated by inositol/choline [Source:SGD;Acc:S000000799] |
| E | YER028C | MIG3 | 26 | -57.9 | 3 | Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes [Source:SGD;Acc:S000000830] |
| E | YER066W | RRT13 | 7 | -16.2 | 3 | Putative protein of unknown function; non-essential gene identified in a screen for mutants with decreased levels of rDNA transcription [Source:SGD;Acc:S000000868] |
| E | YER104W | RTT105 | 47 | -35.6 | 3 | Protein with a role in regulation of Ty1 transposition [Source:SGD;Acc:S000000906] |
| E | YER185W | PUG1 | 16 | -5.9 | 3 | Plasma membrane protein with roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins [Source:SGD;Acc:S000000987] |
| F | YFL011W | HXT10 | 126 | -33 | 3 | Putative hexose transporter, expressed at low levels and expression is repressed by glucose [Source:SGD;Acc:S000001883] |
| F | YFL017W-A | SMX2 | 97 | -23 | 3 | Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G [Source:SGD;Acc:S000002965] |
| F | YFL050C | ALR2 | 164 | -37.4 | 3 | Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000001844] |
| G | YGL010W | MPO1 | 57 | -24.2 | 3 | Putative protein of unknown function; YGL010W is not an essential gene [Source:SGD;Acc:S000002978] |
| G | YGL116W | CDC20 | 80 | -16.8 | 3 | Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate [Source:SGD;Acc:S000003084] |
| G | YGL131C | SNT2 | 72 | -47.1 | 3 | DNA binding protein with similarity to the S. pombe Snt2 protein; computational analysis suggests a role in regulation of expression of genes encoding amine transporters [Source:SGD;Acc:S000003099] |
| G | YGL146C | RRT6 | 14 | -43.5 | 3 | Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; contains two putative transmembrane spans, but no significant homology to other known proteins [Source:SGD;Acc:S000003114] |
| G | YGL154C | LYS5 | 11 | -16.8 | 3 | Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine [Source:SGD;Acc:S000003122] |
| G | YGL176C | YGL176C | 30 | -19.1 | 3 | Putative protein of unknown function; deletion mutant is viable and has no detectable phenotype [Source:SGD;Acc:S000003144] |
| G | YGL209W | MIG2 | 42 | -46.3 | 3 | Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter [Source:SGD;Acc:S000003177] |
| G | YGR026W | YGR026W | 234 | -98.8 | 3 | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery [Source:SGD;Acc:S000003258] |
| G | YGR101W | PCP1 | 32 | -23 | 3 | Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases [Source:SGD;Acc:S000003333] |
| G | YGR105W | VMA21 | 20 | -16.2 | 3 | Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER) [Source:SGD;Acc:S000003337] |
| G | YGR121C | MEP1 | 71 | -32 | 3 | Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation [Source:SGD;Acc:S000003353] |
| G | YGR168C | YGR168C | 166 | -58.1 | 3 | Putative protein of unknown function; YGR168C is not an essential gene [Source:SGD;Acc:S000003400] |
| G | YGR212W | SLI1 | 26 | -90.5 | 3 | N-acetyltransferase, confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin [Source:SGD;Acc:S000003444] |
| H | YHR143W | DSE2 | 15 | -11.7 | 3 | Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP [Source:SGD;Acc:S000001186] |
| H | YHR211W | FLO5 | 35 | -39.2 | 3 | Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p [Source:SGD;Acc:S000001254] |
| I | YIL006W | YIA6 | 11 | -113.6 | 3 | Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs [Source:SGD;Acc:S000001268] |
| I | YIL049W | DFG10 | 15 | -32.2 | 3 | Probable polyprenol reductase that catalyzes conversion of polyprenol to dolichol, the precursor for N-glycosylation; involved in filamentous growth; mutations in human ortholog SRD5A3 confer CDG (Congenital Disorders of Glycosylation) [Source:SGD;Acc:S000001311] |
| I | YIL099W | SGA1 | 27 | -88.6 | 3 | Intracellular sporulation-specific glucoamylase involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation [Source:SGD;Acc:S000001361] |
| I | YIR027C | DAL1 | 51 | -31.3 | 3 | Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression [Source:SGD;Acc:S000001466] |
| J | YJL059W | YHC3 | 13 | -13.8 | 3 | Vacuolar membrane protein involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; homolog of human CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis) [Source:SGD;Acc:S000003595] |
| J | YJL079C | PRY1 | 99 | -43.1 | 3 | Protein of unknown function [Source:SGD;Acc:S000003615] |
| J | YJL113W | YJL113W | 41 | -27.7 | 3 | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes [Source:SGD;Acc:S000003649] |
| J | YJL199C | MBB1 | 19 | -20.1 | 3 | Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies [Source:SGD;Acc:S000003735] |
| J | YJL214W | HXT8 | 129 | -22.1 | 3 | Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose [Source:SGD;Acc:S000003750] |
| J | YJR116W | TDA4 | 19 | -29.5 | 3 | Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele [Source:SGD;Acc:S000003877] |
| J | YJR153W | PGU1 | 13 | -93.1 | 3 | Endo-polygalacturonase, pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins [Source:SGD;Acc:S000003914] |
| K | YKR011C | YKR011C | 37 | -108 | 3 | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus [Source:SGD;Acc:S000001719] |
| K | YKR051W | YKR051W | 43 | -28.6 | 3 | Putative protein of unknown function [Source:SGD;Acc:S000001759] |
| K | YKR102W | FLO10 | 19 | -31.3 | 3 | Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation [Source:SGD;Acc:S000001810] |
| L | YLL052C | AQY2 | 8 | -25 | 3 | Water channel that mediates the transport of water across cell membranes, only expressed in proliferating cells, controlled by osmotic signals, may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains [Source:SGD;Acc:S000003975] |
| L | YLL053C | YLL053C | 51 | -15.7 | 3 | Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin [Source:SGD;Acc:S000003976] |
| L | YLR165C | PUS5 | 15 | -102.7 | 3 | Pseudouridine synthase, catalyzes only the formation of pseudouridine (Psi)-2819 in mitochondrial 21S rRNA; not essential for viability [Source:SGD;Acc:S000004155] |
| L | YLR168C | UPS2 | 38 | -19.1 | 3 | Mitochondrial intermembrane space protein involved in regulation of mitochondrial cardiolipin and phosphatidylethanolamine levels; null has defects in mitochondrial morphology; similar to Ups1p, Ups3p and to human PRELI [Source:SGD;Acc:S000004158] |
| L | YLR254C | NDL1 | 14 | -16.4 | 3 | Homolog of nuclear distribution factor NudE, NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends [Source:SGD;Acc:S000004244] |
| L | YLR307C-A | YLR307C-A | 17 | -71.4 | 3 | Putative protein of unknown function [Source:SGD;Acc:S000028525] |
| L | YLR408C | BLS1 | 22 | -24 | 3 | Putative protein of unknown function; likely member of BLOC complex involved in endosomal cargo sorting; green fluorescent protein (GFP)-fusion protein localizes to the endosome; YLR408C is not an essential gene [Source:SGD;Acc:S000004400] |
| M | YML068W | ITT1 | 35 | -54.7 | 3 | Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins [Source:SGD;Acc:S000004533] |
| M | YML116W | ATR1 | 52 | -33.2 | 3 | Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide [Source:SGD;Acc:S000004584] |
| M | YMR034C | YMR034C | 17 | -8.6 | 3 | Putative transporter, member of the SLC10 carrier family; identified in a transposon mutagenesis screen as a gene involved in azole resistance; YMR034C is not an essential gene [Source:SGD;Acc:S000004637] |
| M | YMR137C | PSO2 | 46 | -81.8 | 3 | Nuclease required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation [Source:SGD;Acc:S000004745] |
| M | YMR195W | ICY1 | 8 | -5.4 | 3 | Protein of unknown function, required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation [Source:SGD;Acc:S000004808] |
| M | YMR274C | RCE1 | 8 | -18.7 | 3 | Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras and the a-factor mating pheromone [Source:SGD;Acc:S000004887] |
| N | YNL083W | SAL1 | 59 | -32.4 | 3 | ADP/ATP transporter; member of the Ca2+-binding subfamily of mitochondrial carriers, with two EF-hand motifs; transport activity of either Sal1p or Pet9p is critical for viability; polymorphic in different S. cerevisiae strains [Source:SGD;Acc:S000005027] |
| N | YNL146W | YNL146W | 7 | -6.2 | 3 | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNL146W is not an essential gene [Source:SGD;Acc:S000005090] |
| N | YNL187W | SWT21 | 14 | -78.9 | 3 | Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats [Source:SGD;Acc:S000005131] |
| N | YNR071C | YNR071C | 26 | -54.4 | 3 | Putative protein of unknown function [Source:SGD;Acc:S000005354] |
| O | YOL026C | MIM1 | 23 | -17.8 | 3 | Mitochondrial protein required for outer membrane protein import; cooperates with Tom70p to import the subset of proteins with multiple alpha-helical transmembrane segments, including Ugo1p, Tom20p, and others; present as an oligomer in the outer me that may create a local environment that facilitates membrane insertion of substrate proteins; also has a role in assembly of Tom20p into the TOM complex [Source:SGD;Acc:S000005386] |
| O | YOL159C | YOL159C | 23 | -20.1 | 3 | Soluble protein of unknown function; deletion mutants are viable and have elevated levels of Ty1 retrotransposition and Ty1 cDNA [Source:SGD;Acc:S000005519] |
| O | YOR005C | DNL4 | 40 | -39.6 | 3 | DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth [Source:SGD;Acc:S000005531] |
| O | YOR025W | HST3 | 62 | -25.2 | 3 | Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism [Source:SGD;Acc:S000005551] |
| O | YOR047C | STD1 | 19 | -11.1 | 3 | Protein involved in control of glucose-regulated gene expression; interacts with kinase Snf1p, glucose sensors Snf3p and Rgt2p, TATA-binding Spt15p; regulator of transcription factor Rgt1p; interactions with Pma1p appear to propagate [GAR+] [Source:SGD;Acc:S000005573] |
| O | YOR060C | SLD7 | 28 | -27.6 | 3 | Protein with a role in chromosomal DNA replication; interacts with Sld3p and reduces its affinity for Cdc45p; deletion mutant has aberrant mitochondria [Source:SGD;Acc:S000005586] |
| O | YOR137C | SIA1 | 28 | -60.5 | 3 | Protein of unassigned function involved in activation of the Pma1p plasma membrane H+-ATPase by glucose [Source:SGD;Acc:S000005663] |
| O | YOR156C | NFI1 | 60 | -54.3 | 3 | SUMO E3 ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; primary E3 ligase for Sir4p; sumoylates Yku70p/Yku80p and Sir4p in vivo to promote chromatin anchoring; promotes telomere anchoring to the nuclear envelope; involved in m ance of proper telomere length [Source:SGD;Acc:S000005682] |
| O | YOR228C | MCP1 | 62 | -64 | 3 | Protein of unknown function, localized to the mitochondrial outer membrane [Source:SGD;Acc:S000005754] |
| O | YOR380W | RDR1 | 37 | -22.6 | 3 | Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins [Source:SGD;Acc:S000005907] |
| O | YOR381W | FRE3 | 12 | -27.5 | 3 | Ferric reductase, reduces siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels [Source:SGD;Acc:S000005908] |
| O | YOR384W | FRE5 | 27 | -160.8 | 3 | Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000005911] |
| O | YOR390W | FEX1 | 53 | -74.5 | 3 | Putative protein of unknown function [Source:SGD;Acc:S000005917] |
| P | YPL024W | RMI1 | 26 | -17.7 | 3 | Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex; stimulates superhelical relaxing and ssDNA binding activities of Top3p; involved in response to DNA damage; null mutants display increased rates of recombination and delayed S phase [Source:SGD;Acc:S000005945] |
| P | YPL052W | OAZ1 | 38 | -45.8 | 3 | Regulator of ornithine decarboxylase (Spe1p), antizyme that binds to Spe1p to stimulate ubiquitin-independent degradation by the proteasome; binding of polyamines to nascent Oaz1p during translation stimulates +1 ribosomal frameshifting, allowing tr ion of full-length Oaz1p [Source:SGD;Acc:S000005973] |
| P | YPL159C | PET20 | 110 | -26.6 | 3 | Mitochondrial protein, required for respiratory growth under some conditions and for stability of the mitochondrial genome [Source:SGD;Acc:S000006080] |
| P | YPL164C | MLH3 | 70 | -124 | 3 | Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability [Source:SGD;Acc:S000006085] |
| P | YPL272C | PBI1 | 27 | -14.6 | 3 | Putative protein of unknown function; gene expression induced in response to ketoconazole; YPL272C is not an essential gene [Source:SGD;Acc:S000006193] |
| P | YPL279C | FEX2 | 52 | -74.5 | 3 | Putative protein of unknown function [Source:SGD;Acc:S000006200] |
| P | YPR009W | SUT2 | 39 | -10.4 | 3 | Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p [Source:SGD;Acc:S000006213] |
| P | YPR061C | JID1 | 32 | -50.1 | 3 | Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae [Source:SGD;Acc:S000006265] |
| P | YPR138C | MEP3 | 54 | -17.3 | 3 | Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation ammonia permease [Source:SGD;Acc:S000006342] |
| P | YPR169W-A | YPR169W-A | 16 | -7.4 | 3 | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B [Source:SGD;Acc:S000028591] |
| Q | Q0055 | AI2 | 44 | -115.2 | 3 | Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene [Source:SGD;Acc:S000007262] |
| Q | Q0070 | AI5_ALPHA | 22 | -61.1 | 3 | Endonuclease I-SceIV, involved in intron mobility; encoded by a mobile group I intron within the mitochondrial COX1 gene [Source:SGD;Acc:S000007265] |
| Q | Q0105 | COB | 89 | -54.1 | 3 | Cytochrome b, mitochondrially encoded subunit of the ubiquinol-cytochrome c reductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p [Source:SGD;Acc:S000007270] |
| Q | Q0110 | BI2 | 89 | -68.6 | 3 | Mitochondrial mRNA maturase with a role in splicing, encoded by both exon and intron sequences of partially processed COB mRNA [Source:SGD;Acc:S000007271] |
| Q | Q0115 | BI3 | 82 | -36.6 | 3 | Mitochondrial mRNA maturase, forms a complex with Mrs1p to mediate splicing of the bI3 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA [Source:SGD;Acc:S000007272] |
| Q | Q0120 | BI4 | 92 | -83.2 | 3 | Mitochondrial mRNA maturase, forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA [Source:SGD;Acc:S000007273] |