The Mediator complex: a master coordinator of transcription and cell lineage development, Jing-wen Yin, Gang Wang, Development 2014 141: 977-987; doi: 10.1242/dev.098392
The following Modification-Abundance (M-A) diagrams show the number of times a residue has been observed with a particular PTM in a peptide-to-spectrum match in GPMDB, as a function of the residue's position in the corresponding protein sequence. Note that the Y-axes have log scales.
| CDK8 module | Middle | Head | Tail | 
 CDK8 module proteins
CDK8 module — CDK8:p, cyclin dependent kinase 8 [GRCh38.p12; HGNC:1779; TSL:1], alt: K35 (details)
CDK8 module — CDK19:p, cyclin dependent kinase 19 [GRCh38.p12; HGNC:19338; TSL:1], alt: KIAA1028, bA346C16.3 (details)
CDK8 module — CCNC:p, cyclin C [GRCh38.p12; HGNC:1581; TSL:1], alt: CycC (details)
CDK8 module — MED12:p, mediator complex subunit 12 [GRCh38.p12; HGNC:11957; TSL:1], alt: CAGH45, HOPA, OPA1, TRAP230, KIAA0192, OKS (details)
CDK8 module — Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) [Source:Uniprot/SWISSPROT;Acc:Q9UHV7] alt: KIAA0593; TRAP240; THRAP1; thyroid hormone receptor associated protein 1 (details)
 Middle proteins
Middle — MED1:p, mediator complex subunit 1 [GRCh38.p12; HGNC:9234; TSL:1], alt: PBP, TRAP220, RB18A, DRIP230, CRSP200, CRSP1 (details)
Middle — MED4:p, mediator complex subunit 4 [GRCh38.p12; HGNC:17903; TSL:1], alt: HSPC126, DRIP36, TRAP36 (details)
Middle — MED7:p, mediator complex subunit 7 [GRCh38.p12; HGNC:2378; TSL:1], alt: CRSP33 (details)
Middle — MED9:p, mediator complex subunit 9 [GRCh38.p12; HGNC:25487; TSL:1], alt: FLJ10193, MED25 (details)
Middle — MED10:p, mediator complex subunit 10 [GRCh38.p12; HGNC:28760; TSL:1], alt: TRG20, L6, MGC5309, NUT2 (details)
Middle — MED14:p, mediator complex subunit 14 [GRCh38.p12; HGNC:2370; TSL:1], alt: EXLM1, CRSP150, TRAP170, RGR1, CSRP (details)
Middle — MED21:p, mediator complex subunit 21 [GRCh38.p12; HGNC:11473; TSL:1], alt: SRB7 (details)
Middle — MED26:p, mediator complex subunit 26 [GRCh38.p12; HGNC:2376; TSL:1], alt: CRSP70 (details)
Middle — MED27:p, mediator complex subunit 27 [GRCh38.p12; HGNC:2377; TSL:1], alt: TRAP37, CRSP34, MED3 (details)
Middle — MED31:p, mediator complex subunit 31 [GRCh38.p12; HGNC:24260; TSL:1], alt: CGI-125, Soh1 (details)
Head — MED6:p, mediator complex subunit 6 [GRCh38.p12; HGNC:19970; TSL:1], alt: NY-REN-28 (details)
Head — MED8:p, mediator complex subunit 8 [GRCh38.p12; HGNC:19971; TSL:5], alt: MGC17544, MGC19641, ARC32 (details)
Head — MED11:p, mediator complex subunit 11 [GRCh38.p12; HGNC:32687; TSL:1], alt: HSPC296, MGC88387 (details)
Head — MED17:p, mediator complex subunit 17 [GRCh38.p12; HGNC:2375; TSL:1], alt: CRSP77, TRAP80, DRIP80, SRB4 (details)
Head — MED18:p, mediator complex subunit 18 [GRCh38.p12; HGNC:25944; TSL:2], alt: FLJ20045, p28b, SRB5 (details)
Head — MED19:p, mediator complex subunit 19 [GRCh38.p12; HGNC:29600; TSL:1], alt: LCMR1 (details)
Head — MED20:p, mediator complex subunit 20 [GRCh38.p12; HGNC:16840; TSL:1], alt: DKFZp586D2223, PRO0213, SRB2 (details)
Head — MED22, mediator complex subunit 22 [Source:HGNC Symbol;Acc:11477;CCDS ID:CCDS6964] (details)
Head — MED28:p, mediator complex subunit 28 [GRCh38.p12; HGNC:24628; TSL:1], alt: EG1, DKFZP434N185, magicin (details)
Head — MED30:p, mediator complex subunit 30 [GRCh38.p12; HGNC:23032; TSL:1], alt: TRAP25 (details)
 Tail proteins
Tail — MED15:p, mediator complex subunit 15 [GRCh38.p12; HGNC:14248; TSL:1], alt: TIG-1, CAG7A, Arc105 (details)
Tail — MED16:p, mediator complex subunit 16 [GRCh38.p12; HGNC:17556; TSL:1], alt: DRIP92, TRAP95 (details)
Tail — MED23:p, mediator complex subunit 23 [GRCh38.p12; HGNC:2372; TSL:1], alt: CRSP130, DRIP130, Sur2 (details)
Tail — MED24:p, mediator complex subunit 24 [GRCh38.p12; HGNC:22963; TSL:1], alt: TRAP100, KIAA0130, DRIP100, CRSP100, MED5 (details)
Tail — MED25:p, mediator complex subunit 25 [GRCh38.p12; HGNC:28845; TSL:1], alt: ARC92, ACID1, TCBAP0758, DKFZp434K0512 (details)
Tail — MED29:p, mediator complex subunit 29 [GRCh38.p12; HGNC:23074; TSL:1], alt: DKFZp434H247, MED2 (details)